Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis

dc.contributor.advisorPepper, Michael Sean
dc.contributor.coadvisorDurandt, Chrisna
dc.contributor.coadvisorAmbele, Melvin
dc.contributor.emailrachel26364@gmail.comen_US
dc.contributor.postgraduateGiles, Rachel
dc.date.accessioned2022-07-25T10:44:43Z
dc.date.available2022-07-25T10:44:43Z
dc.date.created2022
dc.date.issued2022
dc.descriptionDissertation (MSc (Medical Immunology))--University of Pretoria, 2022.en_US
dc.description.abstractThe aim of this project was to develop assays that will allow for high-throughput screening to monitor adipogenesis. Such an assay may be useful for the identification of potential drug targets during the process of adipogenesis, which may result in discovering novel solutions to combat obesity and its related comorbidities. The main question for this study is whether adipogenesis can be assessed in smaller well sizes (such as the 96-well plate) with confidence using the specified methods.en_US
dc.description.availabilityUnrestricteden_US
dc.description.degreeMSc (Medical Immunology)en_US
dc.description.departmentImmunologyen_US
dc.description.sponsorshipNRF Masters Scholarship 2020en_US
dc.identifier.citation*en_US
dc.identifier.doihttps://doi.org/10.25403/UPresearchdata.20348028en_US
dc.identifier.otherS2022
dc.identifier.urihttps://repository.up.ac.za/handle/2263/86431
dc.identifier.uriDOI: 10.25403/UPresearchdata.20348028
dc.language.isoenen_US
dc.publisherUniversity of Pretoria
dc.rights© 2022 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
dc.subjectImmunologyen_US
dc.subjectAssaysen_US
dc.subjectAdipogenesisen_US
dc.subjectDrug targetingen_US
dc.subject96 well plateen_US
dc.subjectUCTD
dc.titleDevelopment of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesisen_US
dc.typeDissertationen_US

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